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They will tell you if it is okay to take Actos with other medicines Uses for Actos. Actos (pioglitazone) is a thiazolidinedione antidiabetic medication used to help control blood sugar levels in people with type 2 diabetes. The Food and Drug Administration approved generic versions of the type 2 diabetes medication Actos (pioglitazone) last week. Actos is used in the treatment of diabetes, type 2 and belongs to the drug class thiazolidinediones. Prescribed for Diabetes - Type 2. [3] It is not recommended in type 1 diabetes. Metformin improves how the body responds to insulin and it is effective for the treatment of type 2 diabetes Pioglitazone Pioglitazone, sold under the brand name Actos among others, is an anti-diabetic medication used to treat type 2 diabetes. 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